EthD-III

EthD-III is a nucleic acid probe. EthD-III is a red fluorescent stain that can be used to detect dead cells. EthD-III enters cells with damaged membranes and binds to nucleic acids, resulting in bright red fluorescence in dead cells (Ex/Em=530/645 nm) [1][2].

Product Specifications

UNSPSC

12171500

Target

DNA Stain

Type

Dye Reagents

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ethd-iii.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

C[NH+](CCC[NH2+]CCC[N+]1=C(C2=CC(N)=CC=C2C3=C1C=C(C=C3)N)C4=CC=CC=C4)CCC[NH2+]CCC[N+]5=C(C6=CC(N)=CC=C6C7=C5C=C(C=C7)N)C8=CC=CC=C8

Molecular Formula

C51H62Cl5N9

Molecular Weight

978.36

References & Citations

[1]Anastassov I, et al. Cytoprotection by endogenous zinc in the vertebrate retina. J Neurochem. 2014 Apr;129 (2) :249-55. |[2]Horie T, et al. OmpA-Like Proteins of Porphyromonas gingivalis Mediate Resistance to the Antimicrobial Peptide LL-37. J Pathog. 2018 Dec 27;2018:2068435.