2-Hydroxyquinoline

2-Hydroxyquinoline is an inhibitor of α-glucosidase and α-amylase with IC50 values of 64.4 µg/mL and 130.5 µg/mL, respectively. 2-Hydroxyquinoline can be used in the study of diabetes[1].

Product Specifications

CAS Number

[59-31-4]

UNSPSC

12352200

Hazard Statement

H302, H315, H318, H335

Target

Amylases; Glycosidase

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/2-hydroxyquinoline.html

Purity

99.89

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C=CC2=CC=CC=C2N1

Molecular Formula

C9H7NO

Molecular Weight

145.16

Precautions

H302, H315, H318, H335

References & Citations

[1]Hwa-Won Lee, et al. 2-Hydroxyquinoline and Its Structural Analogs Show Antidiabetic Effects against α-Amylase and α-Glucosidase. Journal of Applied Biological Chemistry (2015) 58 (1), 1-3.