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MAGL-IN-17

MAGL-IN-17 (Compound) is an inhibitor for MAGL with a Ki of 0.4 μM. MAGL-IN-17 inhibits mouse MAGL and rat MAGL with IC50 of 0.18 and 0.24 μM. MAGL-IN-17 exhibits anti-inflammatory activity in mouse experimental autoimmune encephalitis models[1].

Product Specifications

CAS Number

1643657-35-5

UNSPSC

12352005

Target

MAGL

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/magl-in-17.html

Smiles

O=C(CCCCCC1=CC=C(C2=CC=CC=C2)C=C1)OCC3=CC4=C(C=C3)OCO4

Molecular Formula

C26H26O4

Molecular Weight

402.48

References & Citations

[1]Hernández-Torres G, et al., A reversible and selective inhibitor of monoacylglycerol lipase ameliorates multiple sclerosis. Angew Chem Int Ed Engl. 2014 Dec 8;53 (50) :13765-70.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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