MAGL-IN-17
MAGL-IN-17 (Compound) is an inhibitor for MAGL with a Ki of 0.4 μM. MAGL-IN-17 inhibits mouse MAGL and rat MAGL with IC50 of 0.18 and 0.24 μM. MAGL-IN-17 exhibits anti-inflammatory activity in mouse experimental autoimmune encephalitis models[1].
Product Specifications
CAS Number
1643657-35-5
UNSPSC
12352005
Target
MAGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/magl-in-17.html
Smiles
O=C(CCCCCC1=CC=C(C2=CC=CC=C2)C=C1)OCC3=CC4=C(C=C3)OCO4
Molecular Formula
C26H26O4
Molecular Weight
402.48
References & Citations
[1]Hernández-Torres G, et al., A reversible and selective inhibitor of monoacylglycerol lipase ameliorates multiple sclerosis. Angew Chem Int Ed Engl. 2014 Dec 8;53 (50) :13765-70.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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