PSB-SB-487
PSB-SB-487 is a potent GPR55 antagonist and CB2 agonist with an IC50 value of 0.113 µM for GPR55, and a Ki value of 0.292 µM for human CB2. PSB-SB-487 can be used for researching diabetes, Parkinson’s disease, neuropathic pain, and cancer[1].
Product Specifications
CAS Number
1399049-81-0
UNSPSC
12352005
Target
Cannabinoid Receptor; GPR55
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/psb-sb-487.html
Purity
98.01
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(CC2=CC=CC=C2O)=CC3=C(O)C=C(C(C)(C)CCCCCCC)C=C3O1
Molecular Formula
C26H32O4
Molecular Weight
408.53
References & Citations
[1]Viktor Rempel, et al. Antagonists for the orphan G-protein-coupled receptor GPR55 based on a coumarin scaffold. J Med Chem. 2013 Jun 13;56 (11) :4798-810.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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