L-783483
L-783483 (F3MethylAA) is an agonist for PPARδ. L-783483 ameliorates Carrageenan (HY-125474) -induced paw edema in mice[1].
Product Specifications
CAS Number
[194608-77-0]
Product Name Alternative
F3MethylAA
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/l-783483.html
Smiles
O=C(CC1=CC=C(C(Cl)=C1)SCCCOC2=C(CCC)C(ON=C3C(F)(F)F)=C3C=C2)O
Molecular Formula
C22H21ClF3NO4S
Molecular Weight
487.92
References & Citations
[1]Wan YJ, et al., Inhibition of Carrageenan-Induced Cutaneous Inflammation by PPAR Agonists Is Dependent on Hepatocyte-Specific Retinoid X ReceptorAlpha. PPAR Res. 2006;2006:96341.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARδ
Curated Selection
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