L-783483

L-783483 (F3MethylAA) is an agonist for PPARδ. L-783483 ameliorates Carrageenan (HY-125474) -induced paw edema in mice[1].

Product Specifications

CAS Number

[194608-77-0]

Product Name Alternative

F3MethylAA

UNSPSC

12352005

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/l-783483.html

Smiles

O=C(CC1=CC=C(C(Cl)=C1)SCCCOC2=C(CCC)C(ON=C3C(F)(F)F)=C3C=C2)O

Molecular Formula

C22H21ClF3NO4S

Molecular Weight

487.92

References & Citations

[1]Wan YJ, et al., Inhibition of Carrageenan-Induced Cutaneous Inflammation by PPAR Agonists Is Dependent on Hepatocyte-Specific Retinoid X ReceptorAlpha. PPAR Res. 2006;2006:96341.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PPARδ

Curated Selection

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