Ro60-0175
Ro60-0175 is a potent and selective agonist of 5-HT2C receptor. Ro60-0175 reduces self-administration[1].
Product Specifications
CAS Number
[169675-08-5]
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ro60-0175.html
Concentration
10mM
Purity
99.52
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
N[C@@H](C)CN1C=CC2=C1C=C(Cl)C(F)=C2
Molecular Formula
C11H12ClFN2
Molecular Weight
226.68
References & Citations
[1]Fletcher PJ, et al. The 5-HT2C receptor agonist Ro60-0175 reduces cocaine self-administration and reinstatement induced by the stressor yohimbine, and contextual cues. Neuropsychopharmacology. 2008;33 (6) :1402-1412.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor; α-1 microglobulin
Available Sizes
Curated Selection
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