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α-Amylase/α-Glucosidase-IN-9

α-Amylase/α-Glucosidase-IN-9 (compound 5h) is a dual inhibitor for both α-amylase (IC50 = 16.4 μM) and α-glucosidase (IC50 = 31.6 μM) enzymes[1].

Product Specifications

UNSPSC

12352005

Target

Amylases; Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-amylase-α-glucosidase-in-9.html

Solubility

10 mM in DMSO

Smiles

[O-][N+](C1=CC=C2C(N=C(NCC)C(OCC3=CC(C4=C(Cl)C=CC=C4)=NO3)=N2)=C1)=O

Molecular Formula

C20H16ClN5O4

Molecular Weight

425.83

References & Citations

[1]Mohd Radzuan SN, et al. Synthesis, biological activities, and evaluation molecular docking-dynamics studies of new phenylisoxazole quinoxalin-2-amine hybrids as potential α-amylase and α-glucosidase inhibitors. RSC Adv. 2024;14 (11) :7684-7698. Published 2024 Mar 5.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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