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IDO-IN-6

IDO-IN-6 (NLG-1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, Compound 1486, has an IC50 of <1 μM.

Product Specifications

CAS Number

[1402837-76-6]

Product Name Alternative

NLG-1486

UNSPSC

12352005

Target

Indoleamine 2,3-Dioxygenase (IDO)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/IDO-IN-6.html

Purity

99.80

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O[C@H](CC1)CC[C@]1([H])[C@@H](O)C[C@@H]2N3C(C4=C2C(F)=CC=C4)=CN=C3

Molecular Formula

C18H21FN2O2

Molecular Weight

316.37

References & Citations

[1]Mautino, et al. Preparation of fused imidazole derivatives as IDO inhibitors. From PCT Int. Appl. (2012), 20121018.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

IDO

Available Sizes

Curated Selection

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