AF/LE Purified Anti-Human CD41 Antibody[HIP8]

Product Specifications

Background

CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.

Abbreviation

CD41

Gene ID

3674

UniProt

P08514

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD41 protein

Target

HPA; PPP1R; ITGA2B; BDPLT16; BDPLT2; CD41; CD41B; GP2B; GPIIb; GT; GTA; HPA3; PPP1R93; GPalpha Iib; Integrin alpha-Iib; Platelet membrane glycoprotein Iib; ITGAB; &alpha-IIb integrin-n; BDPLT16; alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex; alpha subunit; antigen CD41; antigen CD41) ; form 2; Integrin; Integrin alpha 2b; Integrin alpha IIb; Integrin alpha-IIb light chain; integrin αIIbβ3; ITA2B; platelet fibrinogen receptor; platelet glycoprotein IIb of IIb/IIIa complex; platelet specific antigen BAK

Clonality

Monoclonal

Clone

HIP8

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Cardiovascular; Immunology; Signal Transduction; Stem Cells

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.