RG-102240
RG-102240 is a ligand for insect ecdysone receptor (EcR), with IC50 of 85 and 13 nM, in wildtype G:CfE (DEF) and its A110P mutant. RG-102240 induces the reporter gene activity of wild-type CfEcR and A110P mutant[1].
Product Specifications
CAS Number
[162326-49-0]
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rg-102240.html
Smiles
O=C(C1=CC=CC(OC)=C1CC)NN(C(C)(C)C)C(C2=CC(C)=CC(C)=C2)=O
Molecular Formula
C23H30N2O3
Molecular Weight
382.50
References & Citations
[1]Kumar MB, et al., A single point mutation in ecdysone receptor leads to increased ligand specificity: implications for gene switch applications. Proc Natl Acad Sci U S A. 2002 Nov 12;99 (23) :14710-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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