RG-102240

RG-102240 is a ligand for insect ecdysone receptor (EcR), with IC50 of 85 and 13 nM, in wildtype G:CfE (DEF) and its A110P mutant. RG-102240 induces the reporter gene activity of wild-type CfEcR and A110P mutant[1].

Product Specifications

CAS Number

[162326-49-0]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/rg-102240.html

Smiles

O=C(C1=CC=CC(OC)=C1CC)NN(C(C)(C)C)C(C2=CC(C)=CC(C)=C2)=O

Molecular Formula

C23H30N2O3

Molecular Weight

382.50

References & Citations

[1]Kumar MB, et al., A single point mutation in ecdysone receptor leads to increased ligand specificity: implications for gene switch applications. Proc Natl Acad Sci U S A. 2002 Nov 12;99 (23) :14710-5.