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FAP Ligand 1

FAP Ligand 1 (FL), a high-affinity FAP small-molecule ligand, is used to target attached drugs to FAP-expressing fibroblasts and can be used in radiation imaging studies of targeted cancers[1].

Product Specifications

CAS Number

[2230625-76-8]

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fap-ligand-1.html

Purity

97.48

Solubility

DMSO : 75 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=NC(CN)=C1)N[C@@H](C)C(N2[C@@H](CC(F)(C2)F)C#N)=O

Molecular Formula

C15H17F2N5O2

Molecular Weight

337.32

References & Citations

[1]Jyoti Roy, et al. Design and validation of fibroblast activation protein alpha targeted imaging and therapeutic agents.Theranostics 2020; 10 (13) :5778-5789.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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