Phospho-MARCKS (Ser167/170) Rabbit APC Conjugate

<strong> Phospho-MARCKS (Ser167/170) Rabbit APC Conjugate</strong>_x000D_ <strong>Catalog number:</strong> B2018884_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 31.56 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8℃_x000D_ <strong>Keywords:</strong> Myristoylated alanine-rich C-kinase substrate, Protein kinase C substrate, PKCSL, 80 kDa protein light chain, MACS, PRKCSL_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Fujise A, Mizuno K, Ueda Y, Osada S, Hirai S, Takayanagi A, Shimizu N, Owada MK, Nakajima H, Ohno S. Specificity of the high affinity interaction of protein kinase C with a physiological substrate, myristoylated alanine-rich protein kinase C substrate J Biol Chem. 1994 Dec 16;269(50):31642-8._x000D_ 2: Yang Y, Chen Y, Saha MN, Chen J, Evans K, Qiu L, Reece D, Chen GA, Chang H. Targeting phospho-MARCKS overcomes drug-resistance and induces antitumor activity in preclinical models of multiple myeloma Leukemia. 2015 Mar;29(3):715-26._x000D_ 3: Liu J, Chen SJ, Hsu SW, Zhang J, Li JM, Yang DC, Gu S, Pinkerton KE, Chen CH. MARCKS cooperates with NKAP to activate NF-kB signaling in smoke-related lung cancer Theranostics. 2021 Feb 19;11(9):4122-4136._x000D_ 4: Chen CH, Cheng CT, Yuan Y, Zhai J, Arif M, Fong LW, Wu R, Ann DK. Elevated MARCKS phosphorylation contributes to unresponsiveness of breast cancer to paclitaxel treatment Oncotarget. 2015 Jun 20;6(17):15194-208._x000D_ 5: Issara-Amphorn J, Sjoelund VH, Smelkinson M, Montalvo S, Yoon SH, Manes NP, Nita-Lazar A. Myristoylated, alanine-rich C-kinase substrate (MARCKS) regulates toll-like receptor 4 signaling in macrophages Sci Rep. 2023 Nov 10;13(1):19562._x000D_ 6: Issara-Amphorn J, Sjoelund V, Smelkinson M, Yoon SH, Manes NP, Nita-Lazar A. Myristoylated, Alanine-rich C-kinase Substrate (MARCKS) regulates Toll-like receptor 4 signaling in macrophages Res Sq [Preprint]. 2023 Jul 10:rs.3.rs-3094036._x000D_ 7: Rodriguez Peña MJ, Castillo Bennett JV, Soler OM, Mayorga LS, Michaut MA. MARCKS protein is phosphorylated and regulates calcium mobilization during human acrosomal exocytosis PLoS One. 2013 May 21;8(5):e64551._x000D_ 8: Beckmann L, Berg V, Dickhut C, Sun C, Merkel O, Bloehdorn J, Robrecht S, Seifert M, da Palma Guerreiro A, Claasen J, Loroch S, Oliverio M, Underbayev C, Vaughn L, Thomalla D, Hülsemann MF, Tausch E, Fischer K, Fink AM, Eichhorst B, Sickmann A, Wendtner CM, Stilgenbauer S, Hallek M, Wiestner A, Zahedi RP, Frenzel LP. MARCKS affects cell motility and response to BTK inhibitors in CLL Blood. 2021 Aug 19;138(7):544-556._x000D_ 9: Ziemba BP, Falke JJ. A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages PLoS One. 2018 May 1;13(5):e0196678._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/23955080">10: Chen CH, Thai P, Yoneda K, Adler KB, Yang PC, Wu R. A peptide that inhibits function of Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) reduces lung cancer metastasis Oncogene. 2014 Jul 10;33(28):3696-706. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-MARCKS (Ser167/170) Rabbit APC Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Conjugates/"> Conjugates</a>