Nerisopam

Nerisopam is an orally active gamma-aminobutyric acid (GABA) receptor agonist. Nerisopam is an anxiolytic and antipsychotic homophthalazine. Nerisopam induces rapid, intense expression of Fos-like immunoreactivity in the rostral, dorsomedial and lateral parts of the striatum in the rat[1].

Product Specifications

CAS Number

[102771-12-0]

Product Name Alternative

GYKI52322; EGIS-6775

UNSPSC

12352005

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nerisopam.html

Solubility

10 mM in DMSO

Smiles

NC1=CC=C(C=C1)C2=NN=C(CC3=CC(OC)=C(C=C32)OC)C

Molecular Formula

C18H19N3O2

Molecular Weight

309.36

References & Citations

[1]Palkovits M, et al. Anxiolytic homophthalazines increase Fos-like immunoreactivity in selected brain areas of the rat. Eur J Pharmacol. 1997 Jul 16;331 (1) :53-63.