Coclaurine
Product Specifications
UNSPSC Description
Coclaurine is a class of tetrahydroisoquinoline alkaloids that can be isolated from Sarcopetalum harveyanum. Coclaurine is a nicotinic acetylcholine receptor (nAChRs) antagonist[1][2].
Target Antigen
nAChR
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/coclaurine.html
Purity
98.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC2=C(C=C1OC)CCN[C@H]2CC3=CC=C(O)C=C3
Molecular Weight
285.34
References & Citations
[1]Sowemimo BO, et al. The isolation of stepharine and coclaurine from Sarcopetalum harveyanum. Lloydia. 1972 Mar;35(1):90-1.|[2]Matthew J. Cheesman . Oceania: Antidepressant Medicinal Plants. Herbal Medicine in Depression. 2016, 483-527.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N3610/Coclaurine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N3610/Coclaurine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
486-39-5
Available Sizes
Curated Selection
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