Recombinant Mouse Csf3 Protein (Trx Tag)
Product Specifications
Background
Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of alpha-helical motifs of the former and two fibronectin type III as well as an immunoglobulin-like domain of the latter. G-CSF is a cytokine that have been demonstrated to improve cardiac function and perfusion in myocardial infarction. And it was initially evaluated as a stem cell mobilizer and erythropoietin as a cytoprotective agent.
Abbreviation
Csf3
Synonyms
CSF; TNFSF; C17orf; C17orf33; CD254; CSF3OS; Filgrastim; GCSF; G-CSF; Granulocyte colony-stimulating factor; Lenograstim; ODF (Osteoclast Differentiation Factor) ; OPGL; Pluripoietin; soluble Receptor Activator of NF-kB Ligand; sRNAK Ligand; TNFSF11; TRANCE (TNF-Related Activation-induced Cytokine) ; Csfg; Csf3
UniProt
P09920
Accession Number
P09920
Expression System
E.coli
Tag
N-Trx
Sequence
Val31-Ala208
Field of Research
Immunology; Cancer; Cell Biology; Signal Transduction; Stem cells
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/xlgxas
Product MSDS
https://789.bio/eb/p90GKC
Calculated Molecular Weight
39.6 kDa
Observed Molecular Weight
35 kDa
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Species
Mouse
Available Sizes
Curated Selection
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