HI-TOPK-032

HI-TOPK-032 is a potent and specific TOPK inhibitor.

Product Specifications

CAS Number

[487020-03-1]

UNSPSC

12352005

Hazard Statement

H302

Target

TOPK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/HI-TOPK-032.html

Purity

98.31

Solubility

DMSO : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CC=CS1)NC2=CC3=C(C#N)C4=NC5=CC=CC=C5N=C4N3C=C2

Molecular Formula

C20H11N5OS

Molecular Weight

369.40

Precautions

H302

References & Citations

[1]Kim DJ, et al. Novel TOPK inhibitor HI-TOPK-032 effectively suppresses colon cancer growth. Cancer Res. 2012 Jun 15;72 (12) :3060-8.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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