HI-TOPK-032
HI-TOPK-032 is a potent and specific TOPK inhibitor.
Product Specifications
CAS Number
[487020-03-1]
UNSPSC
12352005
Hazard Statement
H302
Target
TOPK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/HI-TOPK-032.html
Purity
98.31
Solubility
DMSO : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC=CS1)NC2=CC3=C(C#N)C4=NC5=CC=CC=C5N=C4N3C=C2
Molecular Formula
C20H11N5OS
Molecular Weight
369.40
Precautions
H302
References & Citations
[1]Kim DJ, et al. Novel TOPK inhibitor HI-TOPK-032 effectively suppresses colon cancer growth. Cancer Res. 2012 Jun 15;72 (12) :3060-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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