Abaperidone (hydrochloride)
Product Specifications
UNSPSC Description
Abaperidone hydrochloride is a potent antagonist of 5-HT2A?receptor and dopamine D2 receptor with IC50s of 6.2 and 17 nM.
Target Antigen
5-HT Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/abaperidone-hydrochloride.html
Smiles
O=C1C2=CC=C(C=C2OC=C1CO)OCCCN3CCC(CC3)C4=NOC5=C4C=CC(F)=C5.Cl
Molecular Weight
488.94
References & Citations
[1]Bolós J, et al. 7-[3-(1-piperidinyl)propoxy]chromenones as potential atypical antipsychotics. 2. Pharmacological profile of 7-[3-[4-(6-fluoro-1, 2-benzisoxazol-3-yl)-piperidin-1-yl]propoxy]-3-(hydroxymeth yl)chromen -4-one (abaperidone, FI-8602). J Med Chem. 1998 Dec 31;41(27):5402-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101619A/Abaperidone-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101619A/
Clinical Information
No Development Reported
CAS Number
183849-45-8
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