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Diethylumbelliferyl phosphate

Diethylumbelliferyl phosphate (DEUP), a selective and potent inhibitor of cholesterol esterase, does not inhibit protein kinase activity A in vitro, and it effectively disrupts steroidogenesis by blocking the transport of cholesterol into the mitochondria of steroidogenic cells, with an IC50 of 11.6 μM, potentially limiting dietary cholesterol absorption.

Product Specifications

CAS Number

897-83-6

Product Name Alternative

DEUP

UNSPSC

12352005

Hazard Statement

H300

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/diethylumbelliferyl-phosphate.html

Smiles

O=C1OC2=C(C(C)=C1)C=CC(OP(OCC)(OCC)=O)=C2

Molecular Formula

C14H17O6P

Molecular Weight

312.25

Precautions

P264-P270-P330-P405-P501

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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