Diethylumbelliferyl phosphate
Diethylumbelliferyl phosphate (DEUP), a selective and potent inhibitor of cholesterol esterase, does not inhibit protein kinase activity A in vitro, and it effectively disrupts steroidogenesis by blocking the transport of cholesterol into the mitochondria of steroidogenic cells, with an IC50 of 11.6 μM, potentially limiting dietary cholesterol absorption.
Product Specifications
CAS Number
897-83-6
Product Name Alternative
DEUP
UNSPSC
12352005
Hazard Statement
H300
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/diethylumbelliferyl-phosphate.html
Smiles
O=C1OC2=C(C(C)=C1)C=CC(OP(OCC)(OCC)=O)=C2
Molecular Formula
C14H17O6P
Molecular Weight
312.25
Precautions
P264-P270-P330-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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