A2-Iso5-2DC18
A2-Iso5-2DC18 is a dihydroimidazole-linked lipid, served as potent mRNA delivery vehicle. A2-Iso5-2DC18 can be used for antitumor research, including B16F10 melanoma.[1].
Product Specifications
CAS Number
[2412492-07-8]
UNSPSC
12352005
Target
Liposome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/a2-iso5-2dc18.html
Concentration
10mM
Purity
95.19
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCCCCC/C=C\CCCCCCCC1(C=NC(C(OCC)=O)N1CCCN2CCCC2)CCCCCCC/C=C\CCCCCCCC
Molecular Formula
C47H87N3O2
Molecular Weight
726.21
References & Citations
[1]Miao L, et al. Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation. Nat Biotechnol. 2019 Oct;37 (10) :1174-1185.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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