Isoallolithocholic acid-d2

Isoallolithocholic acid-d2 is the deuterium labeled Isoallolithocholic acid (HY-B0172A) . Isoallolithocholic acid is a T cell regulator and enhances regulatory T cells (Tregs) differentiation[1][2].

Product Specifications

CAS Number

[2410277-69-7]

Product Name Alternative

3β-Hydroxy-5α-cholanic acid-d2

UNSPSC

12352211

Target

Apoptosis; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Autophagy; Metabolic Enzyme/Protease; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Purity

99.28

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CC([2H])([2H])C(O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@@](C[C@H](CC4)O)([H])CC3)C

Molecular Formula

C24H38D2O3

Molecular Weight

378.58

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Hang S, et al. Bile acid metabolites control TH17 and Treg cell differentiation. Nature. 2019 Dec;576 (7785) :143-148.