Copper sulfate pentahydrate, for cell culture, 98%

Copper sulfate pentahydrate, for cell culture, 98% is a biochemical reagent. Copper sulfate pentahydrate, for cell culture, 98% reduces the production of ROS and the expression levels of MyD88 as well as c-Rel genes. Copper sulfate pentahydrate, for cell culture, 98% decreases the activities of T-SOD, CAT, and GSH, increases the activities of caspase-3, caspase-8, and caspase-9. Copper sulfate pentahydrate, for cell culture, 98% is cytotoxic to various cells[1][2][3][4].

Product Specifications

CAS Number

[7758-99-8]

UNSPSC

12352200

Hazard Statement

H302, H318, H410

Target

Biochemical Assay Reagents; Caspase; MyD88; Reactive Oxygen Species (ROS) ; SOD

Type

Biochemical Assay Reagents

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/copper-sulfate-pentahydrate-for-cell-culture-98.html

Purity

98.00

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

[CuSO4?5H2O]

Molecular Formula

CuH10O9S

Molecular Weight

249.69

Precautions

H302, H318, H410

References & Citations

[1]NAKASHIMA, K. et al.Membrane protein cross-linking is an early step in the pathogenesis of copper-induced hemolytic < /b> < b> anemia < /b> Biomedical Research, 1 (6), 548–551. |[2]Feyzi A, et al. Copper sulfate pentahydrate reduced epithelial cytotoxicity induced by lipopolysaccharide from enterogenic bacteria. Biomed Pharmacother. 2017 May;89:454-461. |[3]Wang T, et al. Copper Nanoparticles and Copper Sulphate Induced Cytotoxicity in Hepatocyte Primary Cultures of Epinephelus coioides. PLoS One. 2016 Feb 18;11 (2) :e0149484.|[4]Chaderjian WB, et al. Effect of copper sulfate on performance of a serum-free CHO cell culture process and the level of free thiol in the recombinant antibody expressed. Biotechnol Prog. 2005 Mar-Apr;21 (2) :550-3.