Pongamol
Pongamol (Lanceolatin C) is potent α-glucosidase inhibitor (IC50=103.5 μM) and has free-radical (DPPH) scavenging, antihyperglycemic, and antihyperglycemic activities[1].
Product Specifications
CAS Number
484-33-3
Product Name Alternative
Lanceolatin C
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pongamol.html
Concentration
10mM
Purity
99.81
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(CC(C1=CC=CC=C1)=O)C2=CC=C3OC=CC3=C2OC
Molecular Formula
C18H14O4
Molecular Weight
294.30
Precautions
H302, H315, H319, H335
References & Citations
[1]R Ranga Rao, et al. New furanoflavanoids, intestinal alpha-glucosidase inhibitory and free-radical (DPPH) scavenging, activity from antihyperglycemic root extract of Derris indica (Lam.) . Bioorg Med Chem. 2009 Jul 15;17 (14) :5170-5.|[2]R Ranga Rao, et al. New furanoflavanoids, intestinal alpha-glucosidase inhibitory and free-radical (DPPH) scavenging, activity from antihyperglycemic root extract of Derris indica (Lam.) . Bioorg Med Chem. 2009 Jul 15;17 (14) :5170-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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