Pongamol

Pongamol (Lanceolatin C) is potent α-glucosidase inhibitor (IC50=103.5 μM) and has free-radical (DPPH) scavenging, antihyperglycemic, and antihyperglycemic activities[1].

Product Specifications

CAS Number

[484-33-3]

Product Name Alternative

Lanceolatin C

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/pongamol.html

Concentration

10mM

Purity

99.81

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(CC(C1=CC=CC=C1)=O)C2=CC=C3OC=CC3=C2OC

Molecular Formula

C18H14O4

Molecular Weight

294.30

Precautions

H302, H315, H319, H335

References & Citations

[1]R Ranga Rao, et al. New furanoflavanoids, intestinal alpha-glucosidase inhibitory and free-radical (DPPH) scavenging, activity from antihyperglycemic root extract of Derris indica (Lam.) . Bioorg Med Chem. 2009 Jul 15;17 (14) :5170-5.|[2]R Ranga Rao, et al. New furanoflavanoids, intestinal alpha-glucosidase inhibitory and free-radical (DPPH) scavenging, activity from antihyperglycemic root extract of Derris indica (Lam.) . Bioorg Med Chem. 2009 Jul 15;17 (14) :5170-5.