Anti-Factor V Light Chain Antibody

Mouse Monoclonal Antibody specific to Factor V Light Chain

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

Activated protein C cofactor, Proaccelerin, labile factor [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain]

Gene Name

NCBI Gene ID

UniProt

P12259

Cellular Locus

Secreted

Host

Mouse

Reactivity

Human

Immunogen

Purified human Factor V.

Target Antigen

Coagulation factor V

Target

Factor V Light Chain

Clonality

Monoclonal

Isotype

IgG1

Type

Antibody

Applications

ELISA, IHC, Autorad

Field of Research

Coagulation factors.

Purification Method

Purified by Protein G affinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin.

Additionnal Information

Western blotting: a band of approx. 74kDa is detected.

Storage Conditions

This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.

Specificity

This antibody recognizes the F1F2 polypeptide of human Factor Va light chain.

Formulation

PBS, pH 7.4

Buffer pH

pH 7.4

Target Background

Coagulation cofactor V (Factor V) is a high molecular weight glycoprotein that performs several critical functions in regulating hemostasis. In its thrombin-activated form (FVa) it interacts with Factor Xa and Ca+2 to form the prothrombinase complex. This complex catalyzes the formation of thrombin from prothrombin at rates substantially higher than Factor Xa alone.