Nisotirostide
Product Specifications
UNSPSC Description
Nisotirotide (LY-3457263) is a PYY analog agonist studied in type 2 diabetes and obesity[1].
Target Antigen
Others
Type
Peptides
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/nisotirostide.html
Purity
99.45
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]2N(CCC2)C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H]3N(CCC3)C([C@@H](NC([C@@H](NC([C@H]4N(CCC4)C([C@@H](NC([C@H]5NCCC5)=O)CCCCN)=O)=O)CCC(O)=O)=O)CCCCNC(CCCCCNC([C@@H](NC(CC[C@H](NC(CCCCCCCCCCCCCCCCC(O)=O)=O)C(O)=O)=O)CCC(O)=O)=O)=O)=O)=O)=O)CCC(O)=O)=O)CC(O)=O)=O)C)=O)CO)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CC6=CNC7=C6C=CC=C7)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)CC8=CC=C(C=C8)O)=O)CC9=CC=C(C=C9)O)=O)C)=O)CCC(O)=O)=O)CC(C)C)=O)CCCNC(N)=N)=O)CC%10=CNC=N%10)=O)CC%11=CC=C(C=C%11)O)=O)CC(C)C)=O)CC(N)=O)=O)CC%12=CNC%13=C%12C=CC=C%13)=O)CC(C)C)=O)[C@@H](C)O)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)C(N)=O)C=C1
Molecular Weight
4974.53
References & Citations
[1]Kloock S, et al. Obesity and its comorbidities, current treatment options and future perspectives: Challenging bariatric surgery? Pharmacol Ther. 2023 Nov;251:108549.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10026/Nisotirostide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10026/Nisotirostide-SDS-MedChemExpress.pdf
Clinical Information
Phase 1
CAS Number
2663844-45-7
Available Sizes
Curated Selection
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