Patent Blue V

Patent Blue V (Acid blue 1) is a novel biological dye that can be used as an intraocular dye for retinectomy. Retinectomy refers to the removal of the translucent inner limiting membrane (ILM) . The application of appropriate dyes in vitreoretinal surgery can achieve the purpose of complete removal. Patent Blue V can be used to stain retinal premembranous structures. Spectral analysis shows that Patent Blue V has strong absorption below 450 nm and above 600 nm, showing a blue-green color. Patent Blue V is also used as a marker in lymphangiography for resection of neoplastic lymph nodes[1][2].

Product Specifications

CAS Number

[129-17-9]

Product Name Alternative

Acid blue 1

UNSPSC

12352200

Hazard Statement

H315, H319, H335

Target

Fluorescent Dye

Type

Biochemical Assay Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/patent-blue-v.html

Purity

90.59

Solubility

DMSO : 125 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic)

Smiles

CC/[N+](CC)=C1C=C/C(C=C/1)=C(C2=CC=C(N(CC)CC)C=C2)\C3=CC=C(S(=O)(O[Na])=O)C=C3S(=O)([O-])=O

Molecular Formula

C27H31N2NaO6S2

Molecular Weight

566.66

Precautions

H315, H319, H335

References & Citations

[1]Mennel S, et al. Patent blue: a novel vital dye in vitreoretinal surgery. Ophthalmologica. 2006;220 (3) :190-3. |[2]Barranger E, et al. Laparoscopic sentinel lymph node procedure using a combination of patent blue and radioisotope in women with cervical carcinoma. Cancer. 2003 Jun 15;97 (12) :3003-9.