S0456

S0456 is a raw material that plays a crucial role in the construction of the folate receptor-targeted near-infrared dye OTL 38 (HY-139579) . S0456 is connected to the modified folic acid to form OTL 38, endowing OTL 38 with good optical properties, high affinity, and specificity. S0456 can be used in the research of tumor optical imaging agents[1].

Product Specifications

CAS Number

[1252007-83-2]

UNSPSC

12171500

Target

Drug Intermediate; Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s0456.html

Purity

99.44

Solubility

H2O : 33.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=[S](CCCCN(/C1=C/C=C(CCC2)/C(Cl)=C2/C=C/C(C(C)(C3=C4)C)=[N+](C3=CC=C4[S](=O)([O-])=O)CCCC[S](=O)(O[Na])=O)C(C(C1(C)C)=C5)=CC=C5[S](=O)(O[Na])=O)(O[Na])=O

Molecular Formula

C38H44ClN2Na3O12S4

Molecular Weight

953.44

References & Citations

[1]Mahalingam SM, et al. Evaluation of Novel Tumor-Targeted Near-Infrared Probe for Fluorescence-Guided Surgery of Cancer. J Med Chem. 2018 Nov 8;61 (21) :9637-9646.