RT4I1 rabbit pAb
This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, mental retardation, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Product Specifications
Background
Gene ID
84816
UniProt
Q8WWV3
Cellular Locus
Mitochondrion outer membrane. Colocalizes with the endoplasmic reticulum HSPA5 at spots corresponding to contacts with mitochondria..
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human RT4I1 AA range: 282-332
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1: 500-2000
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES13321-1.pdf
Subcellular Location
Mitochondrion outer membrane . Colocalizes with the endoplasmic reticulum HSPA5 at spots corresponding to contacts with mitochondria. .
Gene ID (Human)
84816
SwissProt (Human)
Q8WWV3
Available Sizes
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