Azeliragon (dihydrochloride)
Azeliragon dihydrochloride (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression with mild Alzheimer’s disease (AD) [1]. Azeliragon dihydrochloride also can cross the blood-brain barrier (BBB) [2].
Product Specifications
CAS Number
[1284150-65-7]
Product Name Alternative
TTP488 (dihydrochloride) ; PF-04494700 (dihydrochloride)
UNSPSC
12352005
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/azeliragon-dihydrochloride.html
Smiles
CCN(CCCOC1=CC=C(C=C1)C2=CN(C(CCCC)=N2)C3=CC=C(C=C3)OC4=CC=C(C=C4)Cl)CC.Cl.Cl
Molecular Formula
C32H40Cl3N3O2
Molecular Weight
605.04
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
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