Autophagy inducer 3
Autophagy inducer 3 has autophagy induced activity. Autophagy inducer 3 possesses robust autophagic cell death in diverse cancer cells sparing normal counterpart. Autophagy inducer 3 induces lethal autophagy by formation of characteristic autophagic vacuoles, LC3 puncta formation, upregulation of signature autophagy markers like Beclin and Atg family proteins[1].
Product Specifications
CAS Number
[2691054-63-2]
UNSPSC
12352005
Target
Atg8/LC3; Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/autophagy-inducer-3.html
Purity
98.02
Solubility
Ethanol : 100 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCCCC[C@H](O)[C@@H](N)CC1=CC=C(C=C1)OC
Molecular Formula
C24H43NO2
Molecular Weight
377.60
References & Citations
[1]Ganesher A, et al. New Spisulosine Derivative promotes robust autophagic response to cancer cells. Eur J Med Chem. 2020;188:112011.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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