Trans-trans-Muconic acid

Trans-trans-Muconic acid is a urinary metabolite of benzene and has been used as a biomarker of exposure to benzene in human. trans-trans-Muconic acid is mutagenic in an E. coli assay[1][2].

Product Specifications

CAS Number

[3588-17-8]

Product Name Alternative

CP 526555

UNSPSC

12352211

Hazard Statement

H315, H319

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/trans-trans-Muconic_acid.html

Purity

99.93

Solubility

DMSO : 33.33 mg/mL (ultrasonic)

Smiles

O=C(O)/C=C/C=C/C(O)=O

Molecular Formula

C6H6O4

Molecular Weight

142.11

Precautions

H315, H319

References & Citations

[1]Bartczak A, ET AL. Evaluation of assays for the identification and quantitation of muconic acid, a benzene metabolite in human urine. J Toxicol Environ Health. 1994 Jul;42 (3) :245-58.|[2]Scherer, G., et al. (1998) . Analysis and evaluation of trans, trans-muconic acid as a biomarker for benzene exposure. Journal of chromatography. B, Biomedical sciences and applications, 717 (1-2), 179–199.