Glycitein

Glycitein is a soy isoflavone used to study apoptosis and antioxidant[1][2][3].

Product Specifications

CAS Number

[40957-83-3]

Product Name Alternative

Glycetein

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Apoptosis; Autophagy

Type

Natural Products

Related Pathways

Apoptosis; Autophagy

Applications

Cancer-programmed cell death

Field of Research

Cancer; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Glycitein.html

Purity

99.72

Solubility

DMSO : 20.83 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C(C1=CC=C(O)C=C1)=CO2)C3=C2C=C(O)C(OC)=C3

Molecular Formula

C16H12O5

Molecular Weight

284.26

Precautions

H315, H319, H335

References & Citations

[1]Song TT, et al. Estrogenic activity of glycitein, a soy isoflavone. J Agric Food Chem. 1999 Apr;47 (4) :1607-10.|[2]Yoshida H, et al. Glycitein effect on suppressing the proliferation and stimulating the differentiation of osteoblastic MC3T3-E1 cells. Biosci Biotechnol Biochem. 2001 May;65 (5) :1211-3.|[3]Pan W, et al. Genistein, daidzein and glycitein inhibit growth and DNA synthesis of aortic smooth muscle cells from stroke-prone spontaneously hypertensive rats. J Nutr. 2001 Apr;131 (4) :1154-8.|[4]Zang YQ, et al. Glycitein induces reactive oxygen species-dependent apoptosis and G0/G1 cell cycle arrest through the MAPK/STAT3/NF-κB pathway in human gastric cancer cells. Drug Dev Res. 2019 Aug;80 (5) :573-584.|[5]Hu YJ, et al. Effect of dietary supplementation with glycitein during late pregnancy and lactation on antioxidative indices and performance of primiparous sows. J Anim Sci. 2015 May;93 (5) :2246-54.|[6]Gutierrez-Zepeda A, et al. Soy isoflavone glycitein protects against beta amyloid-induced toxicity and oxidative stress in transgenic Caenorhabditis elegans. BMC Neurosci. 2005 Aug 25;6:54.