1- (2-Deoxy-2-fluoro-beta-D-arabinofuranosyl) uracil

1- (2-Deoxy-2-fluoro-beta-D-arabinofuranosyl) uracil is a purine nucleoside analogue with antiviral activity[1][2].

Product Specifications

CAS Number

[69123-94-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H320, H335

Target

HSV; Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/1-2-deoxy-2-fluoro-beta-d-arabinofuranosyl-uracil.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NC(C=C1)=O)N1[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2F

Molecular Formula

C9H11FN2O5

Molecular Weight

246.19

Precautions

H302, H315, H320, H335

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.|[2]Watanabe KA, et al., Nucleosides. 110. Synthesis and antiherpes virus activity of some 2'-fluoro-2'-deoxyarabinofuranosylpyrimidine nucleosides. J Med Chem. 1979 Jan;22 (1) :21-4.