SD-70
SD-70 is an inhibitor for histone demethylase JMJD2C and exhibits antitumor efficacy. SD-70 inhibits viability of cancer cells CWR22Rv1 (9% cell survival at 10 μM), PC3 (14% cell survival at 2 μM) and DU145 (26% cell survival at 2 μM) [1].
Product Specifications
CAS Number
332173-89-4
UNSPSC
12352005
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sd-70.html
Purity
99.20
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)C(NC(C1=CC=CO1)C2=CC=C3C=CC=NC3=C2O)=O
Molecular Formula
C18H18N2O3
Molecular Weight
310.35
References & Citations
[1]Xie M, et al., Inhibitors of jmjd2c as anticancer agents. WO2015167874.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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