D-Galactose

D-Galactose is a natural aldohexose and C-4 epimer of glucose.

Product Specifications

CAS Number

[59-23-4]

Product Name Alternative

D- (+) -Galactose

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/D-Galactose.html

Purity

99.85

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 62.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C[C@@H]([C@H]([C@H]([C@@H](CO)O)O)O)O

Molecular Formula

C6H12O6

Molecular Weight

180.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Csiszovszki Z, et al. Structure and function of the D-galactose network in enterobacteria. MBio. 2011 Jun 28;2 (4) :e00053-11.|[2]Cui X, et al. Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidativedamage in mice: protective effects of R-alpha-lipoic acid. J Neurosci Res. 2006 Aug 15;84 (3) :647-54.|[3]Budni J, et al. Oral administration of d-galactose induces cognitive impairments and oxidative damage in rats. Behav Brain Res. 2016 Apr 1;302:35-43.|[4]Haifeng Wei, et al. Behavioural study of the Haifeng Wei, et al. Behavioural study of the D-galactose induced aging model in C57BL/6J mice. Behav Brain Res. 2005, 157, 22.|[5]Saida Haider, et al. A high dose of short term exogenous D-galactose administration in young male rats produces symptoms simulating the natural aging process. Life Sci. 2015.|[6]Wenjing Feng, et al. Alginate Oligosaccharide Prevents against D-galactose-mediated Cataract in C57BL/6J Mice via Regulating Oxidative Stress and Antioxidant System. Curr Eye Res. 2021, 46, 6.|[7]Lei Zhong, et al. Characterization of an i.p. D-galactose-induced cataract model in rats. J Pharmacol Toxicol Methods. 2021.