Antibacterial agent 182
Antibacterial agent 182 (compound 8c) is an antibacterial agent that shows antibacterial activity against various Gram-positive bacteria, particularly against Vancomycin-resistant Enterococcus faecalis (MIC ≤0.125 μg/mL) . Antibacterial agent 182 inhibits biofilm formation of Staphylococcus aureus and Pseudomonas aeruginosa at sub-MIC doses[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-182.html
Solubility
10 mM in DMSO
Smiles
BrC(N1)=C(Br)C(Br)=C1C2=NC(C3=C(O)C(Br)=CC(C(F)(F)F)=C3)=CS2
Molecular Formula
C14H5Br4F3N2OS
Molecular Weight
625.88
References & Citations
[1]Yuanchen Zhong, et al. Design, synthesis and biological evaluation of thiazolyl-halogenated pyrroles or pyrazoles as novel antibacterial and antibiofilm agents. Eur J Med Chem. 2024 Feb 15:268:116221.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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