Hederacolchiside A1
Hederacolchiside A1, isolated from Pulsatilla chinensis, suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway[1]. Hederacolchiside A1 has antischistosomal activity, affecting parasite viability both in vivo and in vitro[2].
Product Specifications
CAS Number
106577-39-3
UNSPSC
12352005
Hazard Statement
H302
Target
Akt; Apoptosis; mTOR; Parasite; PI3K
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/hederacolchiside-a1.html
Purity
99.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@]12[C@]3(C([C@@]4([H])[C@](C(O)=O)(CCC(C)(C)C4)CC3)=CC[C@]1([H])[C@@]5([C@@](C(C)([C@@H](O[C@@]6([H])[C@@H]([C@H]([C@@H](O[C@]7([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)CO)CO6)O)O[C@@]8([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O8)O)O)CC5)C)([H])CC2)C)C
Molecular Formula
C47H76O16
Molecular Weight
897.10
Precautions
H302
References & Citations
Pulsatilla chinensis
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
MTOR; PI3K; Schistosome
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