D-erythro-Sphingosine (hydrochloride)
Product Specifications
UNSPSC Description
D-erythro-Sphingosine (Erythrosphingosine) hydrochloride is a specific TRPM3 activator. D-erythro-Sphingosine also induces retinoblastoma protein dephosphorylation[1][2].
Target Antigen
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d-erythro-sphingosine-hydrochloride.html
Purity
97.0
Solubility
Ethanol : 50 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)CO.[H]Cl
Molecular Weight
335.95
References & Citations
[1]Grimm C, et al. Activation of the melastatin-related cation channel TRPM3 by D-erythro-sphingosine [corrected]. Mol Pharmacol. 2005 Mar;67(3):798-805.|[2]Chao R, et al. Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine. J Biol Chem. 1992 Nov 25;267(33):23459-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W089922/D-erythro-Sphingosine-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W089922/D-erythro-Sphingosine-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2673-72-5
Available Sizes
Curated Selection
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