Mesoridazine
Mesoridazine (TPS-23), a metabolite of Thioridazine , acts as an orally active phenothiazine antipsychotic agent. Mesoridazine is a potent and rapid open-channel blocker of human ether-a-go-go related gene (hERG) channels and blocks hERG currents with an IC50 of 550 nM (at 0 mV) in human embryonic kidney 293 cells[1].Mesoridazine can be used for the research of schizophrenia, as well as certain other psychiatric disorders[1][2].
Product Specifications
CAS Number
5588-33-0
Product Name Alternative
TPS-23
UNSPSC
12352005
Hazard Statement
H225, H302+H312+H332, H319
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mesoridazine.html
Purity
99.48
Solubility
10 mM in DMSO
Smiles
O=S(C(C=C1N2CCC3N(C)CCCC3)=CC=C1SC4=C2C=CC=C4)C
Molecular Formula
C21H26N2OS2
Molecular Weight
386.57
Precautions
H225, H302+H312+H332, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Frequently Asked Questions
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