Boc-Lys (Ac) -AMC

Boc-Lys (Ac) -AMC is a cell-permeable fluorometric HDAC substrate (Ex/Em = 355 nm/460 nm) [1][2].

Product Specifications

CAS Number

[233691-67-3]

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Fluorescent Dye; HDAC

Type

Dye Reagents

Related Pathways

Cell Cycle/DNA Damage; Epigenetics; Others

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/boc-lys-ac-amc.html

Purity

99.53

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C(C(O1)=C2)=CC=C2NC([C@H](CCCCNC(C)=O)NC(OC(C)(C)C)=O)=O)=CC1=O

Molecular Formula

C23H31N3O6

Molecular Weight

445.51

Precautions

H302, H315, H319, H335

References & Citations

[1]Reddy DS, et al. Measuring Histone Deacetylase Inhibition in the Brain. Curr Protoc Pharmacol. 2018 Jun;81 (1) :e41.|[2]Ueki N, et al. Selective cancer targeting with prodrugs activated by histone deacetylases and a tumour-associated protease. Nat Commun. 2013;4:2735.