Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Thymoquinone

Thymoquinone is an orally active natural product isolated from N. sativa Thymoquinone down-regulates the VEGFR2-PI3K-Akt pathway. Thymoquinone has antioxidant, anti-inflammatory, anticancer, antiviral, anticonvulsant, antifungal, antiviral, antiangiogenic activity and hepatoprotective effects. Thymoquinone can be used to study Alzheimer's disease, cancer, cardiovascular disease, infectious disease and inflammation [1][2][3][4][5].

Product Specifications

CAS Number

490-91-5

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Akt; Apoptosis; PI3K; VEGFR

Type

Natural Products

Related Pathways

Apoptosis; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/thymoquinone.html

Purity

99.80

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C(C)=CC(C(C(C)C)=C1)=O

Molecular Formula

C10H12O2

Molecular Weight

164.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Zeinvand-Lorestani H, et al. Protective role of thymoquinone against paraquat-induced hepatotoxicity in mice. Pestic Biochem Physiol. 2018 Jun;148:16-21. |[2]Nagi MN, et al. Protective effect of thymoquinone against doxorubicin-induced cardiotoxicity in rats: a possible mechanism of protection. Pharmacol Res. 2000 Mar;41 (3) :283-9. |[3]Jafri SH, et al. Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo. J Exp Clin Cancer Res. 2010 Jul 1;29 (1) :87.|[4]Elibol B, et al. Thymoquinone administration ameliorates Alzheimer's disease-like phenotype by promoting cell survival in the hippocampus of amyloid beta1-42 infused rat model. Phytomedicine. 2020 Dec;79:153324. |[5]Su X, et al. Thymoquinone inhibits inflammation, neoangiogenesis and vascular remodeling in asthma mice. Int Immunopharmacol. 2016 Sep;38:70-80.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Natural Products

Clinical Information

Phase 3

Isoform

Akt; PI3K; VEGFR2/KDR/Flk-1

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Human 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1) ELISA Kit
orb1665827-01 48 Tests

Human 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1) ELISA Kit

Sign In for Pricing
View Details
Human 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1) ELISA Kit
orb1665827-02 96 Tests

Human 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1) ELISA Kit

Sign In for Pricing
View Details
Recombinant Yersinia pestis bv. Antiqua UPF0761 membrane protein YPA_3514 (YPA_3514)
MBS7041505-01 0.02 mg

Recombinant Yersinia pestis bv. Antiqua UPF0761 membrane protein YPA_3514 (YPA_3514)

Sign In for Pricing
View Details
Recombinant Yersinia pestis bv. Antiqua UPF0761 membrane protein YPA_3514 (YPA_3514)
MBS7041505-02 0.1 mg

Recombinant Yersinia pestis bv. Antiqua UPF0761 membrane protein YPA_3514 (YPA_3514)

Sign In for Pricing
View Details
Recombinant Yersinia pestis bv. Antiqua UPF0761 membrane protein YPA_3514 (YPA_3514)
MBS7041505-03 5x 0.1 mg

Recombinant Yersinia pestis bv. Antiqua UPF0761 membrane protein YPA_3514 (YPA_3514)

Sign In for Pricing
View Details
MRC1 (Macrophage Mannose Receptor 1, MMR, C-type Lectin Domain Family 13 Member D, C-type Lectin Domain Family 13 Member D-like, Macrophage Mannose Receptor 1-like Protein 1, CD206, CLEC13D, CLEC13DL, MRC1L1)
129842 100 µg

MRC1 (Macrophage Mannose Receptor 1, MMR, C-type Lectin Domain Family 13 Member D, C-type Lectin Domain Family 13 Member D-like, Macrophage Mannose Receptor 1-like Protein 1, CD206, CLEC13D, CLEC13DL, MRC1L1)

Sign In for Pricing
View Details