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Ombrabulin (hydrochloride)

Product Specifications

UNSPSC Description

Ombrabulin hydrochloride is a derivative of CA-4 phosphate, which is known to exhibit antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells.

Target Antigen

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Ombrabulin-hydrochloride.html

Purity

99.57

Solubility

DMSO : 100 mg/mL (ultrasonic)|H2O : 20 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC(/C=C\C2=CC(OC)=C(OC)C(OC)=C2)=CC=C1OC)[C@@H](N)CO.[H]Cl

Molecular Weight

438.90

References & Citations

[1]Kim TJ, et al. Antitumor and antivascular effects of AVE8062 in ovarian carcinoma. Cancer Res. 2007 Oct 1;67(19):9337-45.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-18256/Ombrabulin-hydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-18256/Ombrabulin-hydrochloride-SDS-MedChemExpress.pdf

Clinical Information

Phase 3

CAS Number

253426-24-3

Available Sizes

Curated Selection

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