2-Di-1-ASP

2-Di-1-ASP (DASPI; Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA[1].

Product Specifications

CAS Number

[2156-29-8]

Product Name Alternative

DASPI

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

G-quadruplex

Type

Dye Reagents

Related Pathways

Cell Cycle/DNA Damage

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-di-1-asp.html

Purity

99.97

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

C[N+]1=CC=CC=C1/C=C/C2=CC=C(N(C)C)C=C2.[I-]

Molecular Formula

C16H19IN2

Molecular Weight

366.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Xie X, et al. Identification of optimal fluorescent probes for G-quadruplex nucleic acids through systematic exploration of mono- and distyryl dye libraries. Beilstein J Org Chem. 2019 Aug 6;15:1872-1889.