Y4R agonist-2
Y4R agonist-2 is a Y4R agonist with a Ki of 0.033 nM.
Product Specifications
CAS Number
[2757328-63-3]
UNSPSC
12352209
Target
Neuropeptide Y Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/y4r-agonist-2.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](NC(CC1)=O)CCCNC(N)=N)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC2=CC=C(O)C=C2)=O)CCCNC(N)=N)=O)CC(C)C)=O)CCCNC(NC(NCCCCNC1=O)=O)=N)=O)CC3=CNC4=CC=CC=C34
Molecular Formula
C53H81N19O10
Molecular Weight
1144.33
References & Citations
[1]Konieczny A, et al. N-Terminus to Arginine Side-Chain Cyclization of Linear Peptidic Neuropeptide Y Y4 Receptor Ligands Results in Picomolar Binding Constants. J Med Chem. 2021 Nov 8.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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ITGB1 (Beta 1 Subunit, CD 29, CD29, CD29 Antigen, Fibrinogen Receptor beta Subunit, Fibronectin Receptor Subunit beta, FNRB, Glycoprotein IIa, GP IIa, GPIIA, Integrin beta 1 (Fibronectin Receptor beta Polypeptide Antigen CD29 Includes MDF2 MSK12), Integrin beta-1, Integrin VLA 4 Subunit beta, Integrin VLA-4 beta Subunit, Integrin, beta 1 (Fibronectin Receptor, beta Polypeptide, Antigen CD29 Includes MDF2, MSK12), ITGB 1, MDF2, MSK12, Very Late Activation Protein beta Polypeptide, Very Late Activation Protein, beta Polypeptide, VLA Beta, VLA-4 Subunit beta, VLA-Beta, VLAB, VLAbeta)
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