Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Herbacetin (Standard)

Herbacetin (Standard) is the analytical standard of Herbacetin. This product is intended for research and analytical applications. Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects[1]. Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis[2].

Product Specifications

CAS Number

527-95-7

UNSPSC

12352005

Target

Others; Reference Standards

Type

Reference Standards

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/herbacetin-standard.html

Smiles

O=C1C(O)=C(C2=CC=C(O)C=C2)OC3=C(O)C(O)=CC(O)=C13

Molecular Formula

C15H10O7

Molecular Weight

302.24

References & Citations

[1]Veeramani C, et al. Herbacetin, a flaxseed flavonoid, ameliorates high percent dietary fat induced insulin resistance and lipid accumulation through the regulation of hepatic lipid metabolizing and lipid-regulating enzymes. Chem Biol Interact. 2018 May 25;288:49-56.|[2]Kim DJ, et al. Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity. Cancer Res. 2016 Mar 1;76 (5) :1146-1157.|[3]Qian J, Li Y, Zhang X, et al. Herbacetin Broadly Blocks the Activities of CYP450s by Different Inhibitory Mechanisms [published online ahead of print, 2021 Jun 11]. Planta Med. 2021;10.1055/a-1502-7131. |[4]Li L, Fan P, Chou H, Li J, Wang K, Li H. Herbacetin suppressed MMP9 mediated angiogenesis of malignant melanoma through blocking EGFR-ERK/AKT signaling pathway. Biochimie. 2019;162:198-207.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Ddit3 Mouse qPCR Template Standard (NM_007837)
MK200655 1 Kit

Ddit3 Mouse qPCR Template Standard (NM_007837)

Sign In for Pricing
View Details
Compound Fr14262
orb3170199-01 1 mg

Compound Fr14262

Sign In for Pricing
View Details
Compound Fr14262
orb3170199-02 5 mg

Compound Fr14262

Sign In for Pricing
View Details
Dctn1 (NM_001198866) Mouse Tagged ORF Clone
MR231740 10 µg

Dctn1 (NM_001198866) Mouse Tagged ORF Clone

Sign In for Pricing
View Details
NPHP1 Polyclonal Antibody, FITC Conjugated
A53339-100 100 µL

NPHP1 Polyclonal Antibody, FITC Conjugated

Sign In for Pricing
View Details
ACOT6 Polyclonal Antibody
A64966-050 50 µL

ACOT6 Polyclonal Antibody

Sign In for Pricing
View Details