Fleroxacin

Fleroxacin (RO 23-6240) is a broad-spectrum antimicrobial fluoroquinolone.

Product Specifications

CAS Number

[79660-72-3]

Product Name Alternative

RO 23-6240; AM-833

UNSPSC

12352005

Hazard Statement

H302, H315, H320, H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/fleroxacin.html

Purity

99.90

Solubility

0.1 M NaOH : 9.17 mg/mL (ultrasonic; adjust pH to 12 with NaOH) |DMSO : < 1 mg/mL|H2O : 33.33 mg/mL (ultrasonic; adjust pH to 11 with NaOH)

Smiles

O=C(C1=CN(CCF)C2=C(C=C(F)C(N3CCN(C)CC3)=C2F)C1=O)O

Molecular Formula

C17H18F3N3O3

Molecular Weight

369.34

Precautions

H302, H315, H320, H335

References & Citations

[1]Weidekamm, E., et al., Single- and multiple-dose pharmacokinetics of fleroxacin, a trifluorinated quinolone, in humans. Antimicrob Agents Chemother, 1987. 31 (12) : p. 1909-14.|[2]MacDonald, K.S., et al., Evaluation of fleroxacin (RO 23-6240) as single-oral-dose therapy of culture-proven chancroid in Nairobi, Kenya. Antimicrob Agents Chemother, 1989. 33 (5) : p. 612-4.|[3]Rubinstein, E., History of quinolones and their side effects. Chemotherapy, 2001. 47 Suppl 3: p. 3-8; discussion 44-8.