Fleroxacin
Fleroxacin (RO 23-6240) is a broad-spectrum antimicrobial fluoroquinolone.
Product Specifications
CAS Number
79660-72-3
Product Name Alternative
RO 23-6240; AM-833
UNSPSC
12352005
Hazard Statement
H302, H315, H320, H335
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/fleroxacin.html
Purity
99.90
Solubility
0.1 M NaOH : 9.17 mg/mL (ultrasonic; adjust pH to 12 with NaOH) |DMSO : < 1 mg/mL|H2O : 33.33 mg/mL (ultrasonic; adjust pH to 11 with NaOH)
Smiles
O=C(C1=CN(CCF)C2=C(C=C(F)C(N3CCN(C)CC3)=C2F)C1=O)O
Molecular Formula
C17H18F3N3O3
Molecular Weight
369.34
Precautions
H302, H315, H320, H335
References & Citations
[1]Weidekamm, E., et al., Single- and multiple-dose pharmacokinetics of fleroxacin, a trifluorinated quinolone, in humans. Antimicrob Agents Chemother, 1987. 31 (12) : p. 1909-14.|[2]MacDonald, K.S., et al., Evaluation of fleroxacin (RO 23-6240) as single-oral-dose therapy of culture-proven chancroid in Nairobi, Kenya. Antimicrob Agents Chemother, 1989. 33 (5) : p. 612-4.|[3]Rubinstein, E., History of quinolones and their side effects. Chemotherapy, 2001. 47 Suppl 3: p. 3-8; discussion 44-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Quinolone
Available Sizes
Frequently Asked Questions
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