BCH
BCH (2-Amino-2-norbornanecarboxylic acid) is a selective and competitive inhibitor of large neutral amino acid transporter 1 (LAT1) significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis[1][2][3].
Product Specifications
CAS Number
20448-79-7
Product Name Alternative
2-Amino-2-norbornanecarboxylic acid; LAT1-IN-1
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bch.html
Concentration
10mM
Purity
99.13
Solubility
DMSO : < 1 mg/mL|H2O : 20 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1(N)C(C2)CCC2C1)O
Molecular Formula
C8H13NO2
Molecular Weight
155.20
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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